By Amy Norton
MONDAY, Oct. 30, 2017 (HealthDay News) — Acetaminophen can be considered the go-to pain medication during pregnancy. however a brand new study adds to evidence linking the drug to an increased risk of behavioral issues in kids.
Researchers in Norway found of which among nearly 113,000 children, those whose mothers used acetaminophen during pregnancy were slightly more likely to be diagnosed with attention deficit hyperactivity disorder (ADHD).
The link was, however, confined to longer-term use — particularly a month or longer.
When moms used acetaminophen for 29 days or more during pregnancy, their kids were twice as likely to be diagnosed with ADHD, versus women who did not use the drug.
On the some other hand, when expectant moms used the drug for a week or less, their kids showed a slightly decreased risk of ADHD.
Acetaminophen can be best known by the brand name Tylenol, however of which’s an active ingredient in many pain relievers.
The brand new study, led by researcher Eivind Ystrom via the Norwegian Institute of Public Health in Oslo, can be not the first to suggest a connection between prenatal acetaminophen along with also ADHD.
however experts said of which’s still hard to definitively pin the blame on the medication.
“of which’s the dilemma,” said Christina Chambers, co-director of the Center for Better Beginnings at the University of California, San Diego.
Around half of pregnant women use acetaminophen at some point, so of which’s important to understand any risks, according to Chambers, who was not involved inside study.
however having a study like of which, she explained, of which’s difficult to know whether factors some other than acetaminophen are to blame — including the underlying conditions the women had.
According to the study researchers, longer-term use was tied to ADHD whether women used of which for pain, fevers or infections.
however if a woman was using the medications for weeks to treat a fever or infection, of which indicates she was quite ill, Chambers pointed out.
along with also if she took the drug for chronic pain, Chambers said, of which raises the question of what effects the pain condition could have on her pregnancy.
For currently, Chambers stressed of which pregnant women should not be scared off via using acetaminophen for a fever — since an untreated fever could carry risks.
“The last thing we’d want, heading into flu season, can be for women not to use acetaminophen to get a fever down,” she said.
“of which study,” Chambers added, “suggests of which if there can be a causal association between acetaminophen along with also ADHD, of which’s with more-chronic use.”
Overall, more than 2,0 children inside study were diagnosed with ADHD — or about 2 percent of the whole group. The risk was just over twofold higher among kids whose mothers had used acetaminophen for 29 days or more during pregnancy.
Why might the medication affect ADHD risk? There are potential “biologically plausible” explanations, Chambers said.
The drug might, for instance, interfere with maternal hormones of which are important for fetal brain development.
however even if long-term acetaminophen does influence ADHD development, Chambers said, of which study suggests of which’s a “modest” effect.
“The risk to any one woman might be modest,” she said.
of which said, Chambers pointed to a bigger-picture issue: Very few drugs have actually been studied in pregnant women, along with also fairly little can be known about the safety of using any medication prenatally.
The study was published online Oct. 30 inside journal Pediatrics.
Dr. Mark Wolraich, a professor of pediatrics at the University of Oklahoma Health Sciences Center, wrote an editorial accompanying the study.
He agreed of which the study points only to an association between acetaminophen along with also ADHD, which might reflect a “third factor” at play, such as the underlying condition of which caused the women to take the drug.
Plus, Wolraich explained, many factors might affect the development of ADHD. The evidence can be “much stronger” for a familial influence, since the disorder tends to run in families, he noted.
Still, Wolraich said, pregnant women may want to be “overly cautious” about using acetaminophen for any extended time. He suggested of which women talk their doctor before using any medications.
Copyright © 2017 HealthDay. All rights reserved.
SOURCES: Christina Chambers, Ph.D., M.P.H., professor, department of pediatrics, along with also co-director, Center for Better Beginnings, University of California, San Diego; Mark Wolraich, M.D., professor, pediatrics, Child Study Center, University of Oklahoma Health Sciences Center, Oklahoma City; Oct. 30, 2017, Pediatrics, online
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