A fresh drug designed for tackling cancer as well as diabetes has been found to melt away fat of which clogs up arteries.
Researchers by the University of Aberdeen claim of which just just one dose of the fresh drug Trodusquemine can completely reverse the effects of Atherosclerosis. Atherosclerosis is usually the build-up of fatty plaque inside arteries which in turn can cause numerous different heart problems. In particular, the item is usually the condition of which causes heart attacks as well as strokes.
All humans have some level of fatty streaks in their arteries which develop further with age, according to Mirela Delibegovic, a professor at the university, who is usually helping to lead the study.
Her team at the University of Aberdeen tested mice as well as found of which those given either just one a dose or a regular treatment of Trodusquemine, then had less fatty plaques in their arteries.
“These have only been tested at pre-clinical level, in mice, so far yet the results were quite impressive as well as showed of which just just one dose of of which drug seemed to completely reverse the effects of arthrosclerosis,” Delibegovic said.
She added the next step was to conduct human trials.
The drug is usually already undergoing separate trials for treating breast cancer as well as diabetes, where the item inhibits an enzyme called PTP1B.
The researchers found of which the item also stimulated the action of another protein (AMPK), which effectively mimics exercise as well as reduces chronic inflammation.
The £236,000 ($308,000) study to further investigate the drug’s effect on Atherosclerosis was funded by the British Heart Foundation.