By Steven Reinberg
TUESDAY, Oct. 31, 2017 (HealthDay News) — The tiny thyroid gland could have a big impact on heart health, completely new research suggests.
Middle-aged along with older adults with an elevated thyroid hormone may be at higher risk of heart disease along with death, researchers found.
inside the completely new Dutch study, high along with even high-normal levels of a hormone called free thyroxine (FT4) doubled the odds of having calcification of the coronary arteries. This kind of can be a sign of atherosclerosis, commonly called hardening of the arteries.
Higher FT4 levels were also linked to an 87 percent greater risk of having a heart attack or stroke along with twice the risk of dying by one.
“High FT4 is actually indicative of an overactive thyroid,” explained lead researcher Dr. Arjola Bano, of Erasmus University in Rotterdam.
FT4 is actually produced inside the thyroid gland at the front of the neck. This kind of helps control the body’s rate of energy use, she said.
Atherosclerosis means you have fatty deposits called plaque in which can clog arteries. As plaque builds up, the artery narrows, reducing blood flow.
Atherosclerosis can progress by thickening along with hardening of the artery walls to heart disease, stroke along with death, Bano said.
“Our findings suggest in which FT4 measurement can help identify people at increased risk of atherosclerotic events,” she added.
nevertheless before doctors start testing people for their FT4 levels, the findings need confirmation in broader population groups, Bano said. This kind of research was restricted to mostly white participants aged 45 or older.
One doctor who reviewed the findings agreed in which more study is actually needed.
This kind of study shows an association, nevertheless doesn’t prove in which FT4 boosts the risk for heart disease, said Dr. Byron Lee, director of electrophysiology laboratories at the University of California, San Francisco.
“The FT4 could be the cause or simply a marker,” Lee said. “Either way, This kind of warrants further exploration, along with patients with high FT4 should be on the lookout.”
Dr. Minisha Sood is actually an endocrinologist at Lenox Hill Hospital in completely new York City who also reviewed the findings.
She explained in which “thyroid hormone is actually known to boost production of damaging compounds along with to foster an environment inside the body” in which encourages blood clots.
“In an environment of inflammation, which is actually also possibly a contribution by high thyroid hormone levels,” This kind of could help lead to heart disease, Sood said.
nevertheless she too stressed in which the study couldn’t yet prove cause along with effect.
For the study, Bano along with her colleagues tracked data on more than 9,400 participants inside the Rotterdam Study, an ongoing research project inside the Netherlands. Average age of the participants was 65.
The researchers looked at two types of hormones — thyroid-stimulating hormone along with FT4.
They also looked for evidence of atherosclerosis along with death by heart disease, stroke or some other arterial disease.
In addition, they evaluated coronary artery calcification scores, to determine if patients had atherosclerosis without symptoms.
Follow-up averaged nearly nine years. During in which time, 612 patients died of heart disease, while 934 had a heart attack or stroke, the researchers found.
The team concluded in which mechanisms some other than traditional heart risk factors might have played a role in those outcomes. Perhaps preventive measures targeting thyroid function could help reduce heart attack along with stroke rates, they suggested.
The report was published online Oct. 31 inside the journal Circulation Research.
Copyright © 2017 HealthDay. All rights reserved.
SOURCES: Arjola Bano, M.D., M.Sc., D.Sc., researcher, internal medicine along with epidemiology, Erasmus University, Rotterdam, the Netherlands; Byron Lee, M.D., professor, medicine, along with director, electrophysiology laboratories along with clinics, University of California, San Francisco; Minisha Sood, M.D., endocrinologist, Lenox Hill Hospital, completely new York City; Oct. 31, 2017, Circulation Research, online
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